Accurately Measuring Recombination between Closely Related HIV-1 Genomes
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چکیده
منابع مشابه
Accurately Measuring Recombination between Closely Related HIV-1 Genomes
Retroviral recombination is thought to play an important role in the generation of immune escape and multiple drug resistance by shuffling pre-existing mutations in the viral population. Current estimates of HIV-1 recombination rates are derived from measurements within reporter gene sequences or genetically divergent HIV sequences. These measurements do not mimic the recombination occurring in...
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ژورنال
عنوان ژورنال: PLoS Computational Biology
سال: 2010
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1000766